Harry Macklowe, the real estate titan with a career as mercurial as it is long, is riding the wave of successful sales at 432 Park Avenue — said to be the tallest residential building in the Western Hemisphere — and forging ahead with new projects. Sales began this month for a residential condominium in Midtown and he plans to convert One Wall Street, an Art Deco office building, to residential.

“Real estate is a nice thing,” he said. Then, after a brief pause for comic effect, he added: “You can do it until you croak.”

At 80, Mr. Macklowe has had many professional near-deaths over the course of his career, which covers almost six decades and has been marked by dizzying highs and stomach-churning lows. Yet each time, he has pulled off a resurrection. At his latest comeback, 432 Park Avenue, which Macklowe Properties developed with CIM Group, a penthouse sold in September for $87.66 million. The tower proved that Mr. Macklowe continues to be a formidable player in the real estate arena.

His latest project, a condo at 200 East 59th Street, is far more modest, a reflection of the cooling luxury market. The 35-story tower, with 67 apartments, will rise opposite Bloomingdale’s department store. Prices begin at about $2.1 million for a one-bedroom and $4.075 million for a two-bedroom.

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